The Code Page
The best code page that you should choose for your web pages is Unicode.
Navigation and Design Considerations
Some languages force you to apply some changes in the design and navigation of your website.
Font Face Considerations When you are creating your web pages in a language other than English, you would be limited in using font faces.
Despite the language of your web site, the domain name should be in English. At this time, having a domain name in another language presents another set of issues and the way multilingual domain names are handled is still a new issue in development.